
IBS causes are often misunderstood. Many patients continue to suffer despite normal colonoscopy and routine test results. This article uncovers the hidden IBS causes most doctors miss, including gut brain interaction, functional dysregulation, immune involvement, hormonal influences, and post infection changes that explain why irritable bowel syndrome persists and how deeper mechanisms must be addressed.

Irritable Bowel Syndrome affects men and women differently. Hormonal fluctuations, gut–brain signaling, stress response, and digestive motility all shape how IBS symptoms appear, progress, and fluctuate across sexes. Understanding these differences helps explain why some patients experience constipation, others diarrhea, and why symptoms vary across life stages.


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